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DeCS
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Descriptor English:
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Spheroids, Cellular
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Descriptor Spanish:
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Esferoides Celulares
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Descriptor Portuguese:
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Esferoides Celulares
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Synonyms English:
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Cellular Spheroid
Cellular Spheroids
Multicellular Spheroid
Multicellular Spheroids
Spheroid, Cellular
Spheroid, Multicellular
Spheroids, Multicellular
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Tree Number:
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A11.251.800
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Definition English:
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Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4) |
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Indexing Annotation English:
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do not confuse with "spheroid bodies" referring to axons in neuropathol; if tumor spheroids coordinate with TUMOR CELLS, CULTURED
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History Note English:
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2004(1996)
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Allowable Qualifiers English:
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Record Number:
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32606
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Unique Identifier:
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D018874
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Occurrence in VHL:
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Similar:
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DeCS
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